A double helix is the spiraling, twisted-ladder structure of deoxyribonucleic acid (DNA), a fundamental molecule in biology. Discovered by James Watson and Francis Crick, this structure consists of two polynucleotide strands running in opposite directions (antiparallel), with a sugar-phosphate backbone on the outside and paired nitrogenous bases forming the internal "rungs" of the ladder. The complementary base pairing (A with T, and C with G) is essential for how DNA stores genetic information and replicates itself. Components of the DNA Double Helix Two Strands: The molecule is composed of two long, linear strands. Antiparallel Orientation: These two strands run in opposite directions, with their 5' and 3' ends oriented in opposite directions. Sugar-Phosphate Backbones: The outer framework of the helix is formed by alternating sugar (deoxyribose) and phosphate groups. Base Pairs: The inner "rungs" are formed by the four nitrogenous bases: adenine (A), thymine (T), guanine (G), and cytosine (C). Hydrogen Bonds: Adenine always pairs with thymine (A-T), and guanine always pairs with cytosine (G-C), held together by hydrogen bonds. Function and Significance Genetic Information: The sequence of these base pairs stores the genetic code, which directs the chemical processes within cells. Replication: The double helix structure, with its complementary base pairing, is crucial for DNA replication, allowing genetic information to be accurately copied. Evolution: The structure explains both the stability of life over generations and the mutability required for evolution through changes in the base sequence. Modern Biology: The discovery of the double helix was a landmark event, leading to the development of modern molecular biology and the biotechnology industry, including techniques like genetic engineering and DNA fingerprinting.

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